Gastrointestinal dysfunction in the critically ill: a systematic scoping...
AbstractBackgroundGastrointestinal (GI) dysfunction is frequent in the critically ill but can be overlooked as a result of the lack of standardization of the diagnostic and therapeutic approaches. We...
View ArticleBiomarkers in critical care nutrition
AbstractThe goal of nutrition support is to provide the substrates required to match the bioenergetic needs of the patient and promote the net synthesis of macromolecules required for the preservation...
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Omega-6 sparing effects of parenteral lipid emulsions—an updated systematic...
AbstractBackgroundParenteral lipid emulsions in critical care are traditionally based on soybean oil (SO) and rich in pro-inflammatory omega-6 fatty acids (FAs). Parenteral nutrition (PN) strategies...
View ArticleBaseline characteristics and outcome for aneurysmal versus non-aneurysmal...
AbstractThis study aims to investigate the characteristics of patients with mild aneurysmal and non-aneurysmal perimesencephalic and non-perimesencephalic subarachnoid hemorrhage (aSAH, pmSAH, npmSAH)...
View ArticleErfassung und apparatives Monitoring des Ernährungsstatus von Patient*innen...
ZusammenfassungDie Erhebung des Ernährungsstatus zum Zeitpunkt der Aufnahme im Intensiv- oder Intermediate Care Bereich hat sowohl prognostische als auch therapeutische Relevanz im Hinblick auf die...
View ArticleSLPI - a Biomarker of Acute Kidney Injury after Open and Endovascular...
AbstractAcute kidney injury (AKI) is a relevant complication following thoracoabdominal aortic aneurysm repair (TAAA). Biomarkers, such as secretory leucocyte peptidase inhibitor (SLPI), may enable a...
View ArticleAdministration of vitamin D and its metabolites in critically ill adult...
AbstractBackgroundThe clinical significance of vitamin D administration in critically ill patients remains inconclusive. The purpose of this systematic review with meta-analysis was to investigate the...
View ArticleClinical nutrition issues in 2022: What is missing to trust supplemental...
AbstractA multidisciplinary group of international physicians involved in the medical nutrition therapy (MNT) of adult critically ill patients met to discuss the value, role, and open questions...
View ArticleSupplementierung von Vitamin C und D bei kritisch Kranken
ZusammenfassungDer Supplementierung von Mikronährstoffen als Bestandteil der medizinischen Ernährungstherapie kritisch kranker PatientInnen auf der Intensivstation fand in den letzten Jahren zunehmend...
View ArticleIntravenous vitamin C monotherapy in critically ill patients: a systematic...
AbstractBackgroundA recent landmark randomized controlled trial (RCT) in septic patients demonstrated an increased risk of death and persistent organ dysfunction with intravenous Vitamin C (IVVC)...
View ArticleLaborchemisches und kalorimetrisches Monitoring der medizinischen...
ZusammenfassungDieses zweite Positionspapier der Sektion Metabolismus und Ernährung der Deutschen Interdisziplinären Vereinigung für Intensiv- und Notfallmedizin (DIVI) gibt Empfehlungen zum...
View ArticleDecrease of renal resistance during hypothermic oxygenated machine perfusion...
AbstractHypothermic oxygenated machine perfusion (HOPE) was recently tested in preclinical trials in kidney transplantation (KT). Here we investigate the effects of HOPE on extended-criteria-donation...
View ArticleEndoplasmic reticulum stress and the unfolded protein response in skeletal...
AbstractWe provide a descriptive characterization of the unfolded protein response (UPR) in skeletal muscle of human patients with peritoneal sepsis and a sepsis model of C57BL/6J mice. Patients...
View ArticleMapping the cardiac vascular niche in heart failure
AbstractThe cardiac vascular and perivascular niche are of major importance in homeostasis and during disease, but we lack a complete understanding of its cellular heterogeneity and alteration in...
View ArticleThe impact of higher protein dosing on outcomes in critically ill patients...
AbstractBackgroundBased on low-quality evidence, current nutrition guidelines recommend the delivery of high-dose protein in critically ill patients. The EFFORT Protein trial showed that higher protein...
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Identifying a target group for selenium supplementation in high-risk cardiac...
AbstractBackgroundRecent data from the randomized SUSTAIN CSX trial could not confirm clinical benefits from perioperative selenium treatment in high-risk cardiac surgery patients. Underlying reasons...
View ArticleThe effects of higher versus lower protein delivery in critically ill...
AbstractBackgroundA recent large multicentre trial found no difference in clinical outcomes but identified a possibility of increased mortality rates in patients with acute kidney injury (AKI)...
View ArticleEnhanced exclusive enteral nutrition delivery during the first 7 days is...
AbstractBackground and aimsExclusive enteral nutrition (EN) is often observed during the first week of ICU admission because of the extra costs and safety considerations for early parenteral nutrition....
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